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Egyptian Journal of Medical Human Genetics [The]. 2016; 17 (1): 63-70
in English | IMEMR | ID: emr-176215

ABSTRACT

Background: Attention deficit hyperactivity disorder [ADHD] is a common neurodevelopmental disorder with associated mineral deficiency


Aim: To assess magnesium level in ADHD children and compare it to the normal levels in children. Then, to detect the effect of magnesium supplementation as an add on therapy, on magnesium deficient patients


Methods: The study was conducted on 25 patients with ADHD and 25 controls. All subjects had magnesium estimation in serum and hair. ADHD children were further assessed by Wechsler intelligence scale for children, Conners' parent rating scale, and Wisconsin card sorting test. Then magnesium deficient patients were assigned into 2 groups, those who received magnesium, and those who did not. The difference between the studied groups was assessed by Conners' parents rating scale and Wisconsin card sorting test


Results: Magnesium deficiency was found in 18 [72%] of ADHD children. The magnesium supplemented group improved as regards cognitive functions as measured by the Wisconsin card sorting test and Conners' rating scale. The patients reported minor side effects from magnesium supplementation


Conclusion: Magnesium supplementation in ADHD, proves its value and safety


Subject(s)
Humans , Male , Female , Child , Adolescent , Magnesium/therapeutic use , Child , Case-Control Studies , Prospective Studies , Magnesium/blood , Magnesium Deficiency
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